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Pairing this with Thrumming Stone in Commander might seem like the obvious thing to do, but the fact that this exists as an option shows just how popular red is to EDH players

A reprint would hit this card pretty hard, as its not in high demand anywhere

This doesn't automatically make it valuable, but a rare and/or reverse holographic is certainly worth setting aside and looking into further

Imagine a blue instant which mutates all of a players creatures into one, or a Reanimate that mutates a creature from your graveyard onto one you have in play

Perhaps that common is a powerful card in its own right, like Lightning Bolt