mtg miirym commander deck Miirym, Sentinel Wyrm (#2500) (foil) (borderless) Miirym, Sentinel Wyrm. Go Big

If your deck's key engine is a 4cmc commander like Kaalia of the Vast, for example, then you will want to run ramp cards that can get her out faster, which means ramp that is between 0-2cmc so you can cast Kaalia on turn 3 or earlier instead of her usual turn 4

Then, it has both trample and hexproof, ensuring that at least some damage is going to slip through your opponents defenses, and making it awfully difficult to remove outside of combat

Combine it with other cards to give you benefits (or punish opponents) on card draws, and you may have a tasty combo going

Or it could be used in green with

So there should be no differences to the cards or packs