The only thing this shuts down for this is deck Radiant Greninja and Acreus VSTAR ability
To my knowledge, there had never been a card with nothing in the way of rules or flavor text (purposefully textless variants, like promo Lightning Bolts, notwithstanding) before the Gorehorn, and nothing since
The burning cat can close out games quickly once you get their life total low, and dsk-157-screaming-nemesis further shuts down life gain, which a lot of other top decks have in some form
Sword of the Animist and Land Tax both help you to get more land into play, but more importantly, they help thin your deck so that you can find more important cards to advance your strategy
In a meta full of removal and combat, Vren turns every kill into your army