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Formula: C18H15ClN6OS2
Degarelix acetate
PubMed PMID: 27235137
including humans
[Epub ahead of print] PubMed PMID: 27923910
TWS119 Size:10mg solid Formula: C18H15ClN6OS2TWS 119 is a potent and selective inhibitor of glycogen synthase kinase 3 (IC50 = 30 nM). TWS119 could activate Wnt catenin pathway and up regulate the expression of CD62L in a dose dependent manner, but it decreased the expression of CD107a. Glycogen synthase kinase (GSK) 3, a constitutively active serine threonine kinase, acts as a key regulator of major signaling pathways, including the Wnt, Hedgehog, and Notch pathways. Product information CAS