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31-decaoxo-5
InChi: InChI=1S/C18H14N4/c1-12-5-4-8-17(21-12)18-15(11-20-22-18)13-9-10-19-16-7-3-2-6-14(13)16/h2-11H
08 mL) paw swelling as well as total inhibition of the lesion score
4 days) has a tumor:plasma exposure ratio of 12:1 over 24 hours and leads to increased levels of pAkt in tumor tissue
InChi: InChI=1S/C49H66N12O6S/c1-29(2)23-39(45(64)57-38(43(51)62)20-22-68-4)58-46(65)40(25-31-27-55-36-18-10-8-15-33(31)36)59-47(66)42(24-30-13-6-5-7-14-30)61(3)48(67)41(26-32-28-56-37-19-11-9-16-34(32)37)60-44(63)35(50)17-12-21-54-49(52)53/h5-11
LSP-249 hosphocholine 31-decaoxo-5LSP 249 (example 35), extracted from patent WO2016011209A1, is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell. Product information CAS Number: 1801253 04 2 Molecular Weight: 431. 92 Formula: C24H22ClN5O Chemical Name: N [(6 amino 2,4 dimethylpyridin 3 yl)methyl] 2 [(3 chloroquinolin 6 yl)methyl]pyridine 4 carboxamide Smiles: CC1=CC(N)=NC(C)=C1CNC(=O)C1=CC(CC2=CC3=CC(Cl)=CN=C3C=C2)=NC=C1 InChiKey:
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