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17)/t14-/m1/s1
Solubility: DMSO : 50 mg/mL (101
One-step ¹⁸F-labeling of carbohydrate-conjugated octreotate-derivatives containing a silicon-fluoride-acceptor (SiFA): in vitro and in vivo evaluation as tumor imaging agents for positron emission tomography (PET)
is characterized by the presence of an oxime function
Smiles: CCCN1CCC(CC1)C1C=C(C=CC=1)S(C)(=O)=O
Daclatasvir (BMS-790052) 12190 17)/t14-/m1/s1Daclatasvir, formerly known as BMS 790052, is a potent NS5A inhibitor with EC50 values varying from 9 to 146 pM. [1,2] The nonstructural 5A (NS5A) is a target in HCV drug development, which is a 447 amino acid, zinc binding phosphoprotein who plays an essential but enigmatic role in the virus life cycle. However the function of NS5A has no enzymatic activities, which makes it very difficult to understand the antiviral function of daclatasvir. It is