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natriuretic and K+ and Cl- sparing effect of Fr•EtOAc in rats
Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is an effective antibiotic with an MIC90 of 0
InChi: InChI=1S/C19H22N2O2/c1-23-18-10-6-5-9-17(18)20-11-13-21(14-12-20)19(22)15-16-7-3-2-4-8-16/h2-10H
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InChi: InChI=1S/C19H21NO5S/c1-11-8-15(21)18(19(22)25-11)14-10-17(26-7-6-20-14)13-5-4-12(23-2)9-16(13)24-3/h4-5
SAR-020106 22279 natriuretic and K+ and Cl-SAR 020106 is an ATP competitive, potent, and selective CHK1 inhibitor with an IC50 of 13. 3 nM for human CHK1. SAR 020106 shows excellent selectivity over CHK2. SAR 020106 significantly enhances the cell killing of Gemcitabine and SN38 by 3 to 29 fold in several colon tumor lines and in a p53 dependent fashion. SAR 020106 can enhance antitumor activity with selected anticancer drugs. Product information CAS Number: 1184843 57 9 Molecular Weight: 382.
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