Trk-IN-4 Catalog No.:M30790-C Smiles: CC(C)(C)CC1NN=C2NC3CC(C)(C)CC(=O)C=3[C@](C)(C2=1)C1C=CC=CC=1

Smiles: CC(C)(C)CC1NN=C2NC3CC(C)(C)CC(=O)C=3[C@](C)(C2=1)C1C=CC=CC=1

4)24(30)32-20-11-16(23(28)29)10-15-7-6-14(2)19(22(15)20)9-8-18-12-17(26)13-21(27)31-18/h6-7

Smiles: OC(=O)CCOCCOCCOCCOCCNC1C=C2C(=CC=1)C(=O)N(C1CCC(=O)NC1=O)C2=O

AZD-5991 Racemate is a Mcl-1 inhibitor with an IC50 of <3 nM in FRET assay

InChiKey: WDKPRHOCWKLQPK-ZUHYDKSRSA-N

Trk-IN-4 Catalog No.:M30790-C Smiles: CC(C)(C)CC1NN=C2NC3CC(C)(C)CC(=O)C=3[C@](C)(C2=1)C1C=CC=CC=1Trk IN 4 (PF 6683324 isomer) is a potent pan Trk inhibitor in cell based assays with IC50s of 1. 9 nM, 2. 6 nM and 1. 1 nM for TrkA, TrkB and TrkC, respectively. Anti hyperalgesic effect. Product information CAS Number: 1799788 94 5 Molecular Weight: 521. 46 Formula: C24H23F4N5O4 Chemical Name: 2 {[(3S,4R) 3 fluoro 1 {2 [4 (trifluoromethoxy)phenyl]acetyl}piperidin 4 yl]oxy} 5 (1 methyl 1H imidazol 4 yl)pyridine 3 carboxamide Smiles: