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Pixantrone (dimaleate) Catalog No.:M9764-10 In the anesthetized guinea pigs

SKU: 9378446662

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Description

In the anesthetized guinea pigs

Lersivirine is able to inhibit HIV-1 virus replication in MT-2 cells infected with wt NL4-3

The short-term suppression of cell functions is followed by a significant temporary increase of specific growth rate and of specific production rate

has minimum 32-fold selectivity against BRD9

InChi: InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28

Pixantrone (dimaleate) Catalog No.:M9764-10 In the anesthetized guinea pigsPixantrone is a synthetic, noncardiotoxic aza anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Pixantrone is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non Hodgkin lymphoma (aNHL). Product information CAS Number:

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