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InChi: InChI=1S/C22H21N8O8PS4
23)/b11-6+
11(5):524-34
GLPG0187 is a potent inhibitor of osteoclastic bone resorption and angiogenesis
InChi: InChI=1S/C19H22O4/c1-12(2)9-10-22-15-7-5-14(6-8-15)17-16(11-13(3)4)18(20)23-19(17)21/h5-9
SR-717 lithium - CAS# 2375421-09-1 60295 InChi: InChI=1S/C22H21N8O8PS4SR 717 lithium, CAS No. 2375421 09 1, is an agonist of stimulator of interferon genes STING for treating cancer. SR 717 demonstrates broad interspecies and interallelic specificity. SR 717 functions as a direct cyclic guanosine monophosphate adenosine monophosphate (cGAMP) mimetic that induces the same "closed" conformation of STING. SR 717 displayed antitumor activity; promoted the activation of CD8+ T, natural killer, and dendritic cells in relevant
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