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WRW4 inhibits Abeta42 peptide-induced superoxide generation and chemotactic migration of neutrophils
with IC50s of 10 nM and 742 nM for CYP1B1 and CYP1A1
0075 and 0
5E)-1-benzyl-3
2015 Oct 30
GNE-8324 antolactone WRW4 inhibits Abeta42 peptide-induced superoxideGNE 8324 is a selective GluN2A positive allosteric modulator. GNE 8324 selectively enhances NMDA receptor (NMDAR) mediated synaptic responses in inhibitory but not excitatory neurons. Product information CAS Number: 1698901 76 6 Molecular Weight: 343. 42 Formula: C18H18FN3OS Chemical Name: 10 {[ethyl(4 fluorophenyl)amino]methyl} 7 thia 1,9 diazatricyclo[6. 4. 0. 0,]dodeca 2(6),8,10 trien 12 one Smiles: CCN(CC1=CC(=O)N2C(=N1)SC1CCCC2=1)C1C=CC(F)=CC=1
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