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1-4H3/t16-
CAS Number: 1792999-26-8
whereas both PI3Kα and PI3Kβ are relatively unaffected (IC50 values >1 μM)
Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the cell cycle and interferes with the formation of the mitotic spindle
PubMed PMID: 25108436
Masitinib Size:2mg solid 1-4H3/t16-Masitinib, also known as AB1010, is an orally bioavailable and multi targeted protein tyrosine kinase inhibitor with potential antineoplastic activity. Masitinib selectively binds to and inhibits both the wild type and mutated forms of the stem cell factor receptor (c Kit; SCFR); platelet derived growth factor receptor (PDGFR); fibroblast growth factor receptor 3 (FGFR3); and, to a lesser extent, focal adhesion kinase (FAK). As a consequence, tumor
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