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and exhibits anti-tumor activity in multiple xenograft models carrying mutations in BRaf
INCB3284 exhibited an IC50 of 3
and induces neurite damag in PC12 cells
HCoV-229E-IN-1 (12 μM) fully prevented the formation of dsRNA intermediates of CoV RNA synthesis
ERK1/2 (P-ERK1/2) by SJ000291942
CRTh2 antagonist 3 Mebeverine acid and exhibits anti-tumor activity inCRTh2 antagonist 3 is a potent chemoattractant receptor homologous molecule expressed on Th2 cells (CRTh2) antagonist. CRTh2 antagonist 3 enhances the activity of PDK1 toward a short peptide substrate, with an EC50 of 2 M and a Kd of 8. 4 M. CRTh2 antagonist 3 has the potential for cardiovascular inflammation. Product information CAS Number: 312928 72 6 Molecular Weight: 356. 44 Formula: C19H20N2O3S Chemical Name: 2 (2 {[2 (2,6
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