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SR9011 was used at 5-10 µM concentration in vitro and in cellular assays
Chemical Name: N-cyclohexyl-3-{[2-(3
1-20 µM) shows only 13% inhibition on PKC-ι at 20 μM
Triptonide
2172819-77-9
ONO-AE3-208 Size:Solid 2 mg SR9011 was used at 5-10ONO AE3 208 is a potent n EP4 antagonist (Ki = 1. 3 nM). ONO AE3 208 suppresses cell invasion, migration, and metastasis of prostate cancer. The in vitro cell invasion and migration were suppressed by ONO AE3 208 in a dose dependent manner without affecting cell proliferation. The in vivo bone metastasis of PC3 was also suppressed by ONO AE3 208 treatment. EP4 expression levels were correlated with prostate cancer cell invasiveness and EP4 specific
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