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PubMed PMID: 22985969
PPAR-α activation reduced LPS-induced inflammation in alveolar epithelial cells
InChiKey: ZDXPYRJPNDTMRX-UHFFFAOYSA-N
the major human plasma metabolite of gefitinib
Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1
(S, R, S)-AHPC-Me dihydrochloride 0275 PubMed PMID: 22985969(S,R,S) AHPC Me dihydrochloride (VHL ligand 2 dihydrochloride) is the (S,R,S) AHPC based VHL ligand used in the recruitment of the von Hippel Lindau (VHL) protein. (S,R,S) AHPC Me dihydrochloride can be used to synthesize ARV 771, a von Hippel Landau (VHL) E3 ligase based BET PROTAC degrader. ARV 771 potently degrades BET protein in castration resistant prostate cancer (CRPC) cells with a DC50 <1 nM. Product information Molecular Weight: 517. 51
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