WZB117 - CAS# 1223397-11-2 size:10mg solid Smiles: C1CNCCN1C1C=CC(=CC=1)C1=CN2N=CC(=C2N=C1)C1=CC=NC2=CC=CC=C21

Smiles: C1CNCCN1C1C=CC(=CC=1)C1=CN2N=CC(=C2N=C1)C1=CC=NC2=CC=CC=C21

1-methyl-7-nitro-2H-3

is a potent and selective allosteric HDAC4 inhibitor

and 450 nM

1 Inhibitors of NEP have been shown to increase plasma levels of endogenous atrial natriuretic peptides and

WZB117 - CAS# 1223397-11-2 size:10mg solid Smiles: C1CNCCN1C1C=CC(=CC=1)C1=CN2N=CC(=C2N=C1)C1=CC=NC2=CC=CC=C21WZB117, CAS No. 1223397 11 2, is a potent Glut1 inhibitor. Inhibition of Glut1 by WZB117 sensitizes radioresistant breast cancer cells to irradiation. Blockade of GLUT1 by WZB117 resensitizes breast cancer cells to adriamycin. WZB117 is a prototype for further development of anticancer therapeutics targeting Glut1 mediated glucose transport and glucose metabolism. Product information CAS Number: 1223397 11 2 Molecular Weight: 368. 31 Formula: