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InChi: InChI=1S/C27H36N4O5S/c1-6-37(34
BAY11-7082 also reversibly activates MAPK signaling and induces apoptosis of leukemic T cell and B-cell lymphoma cell lines
memory consolidation is inherently limited by the ISR
It inhibits PHD2 with an IC50 ~21 nM
WO 2003077914
ADC Toxin Monomethyl auristatin E (MMAE) - CAS# 474645-27-7 60023 InChi: InChI=1S/C27H36N4O5S/c1-6-37(34Monomethyl auristatin E (MMAE, vedotin), CAS No. 474645 27 7, is a very potent anti mitotic agent that inhibits cell division by blocking the polymerisation of tubulin. Because of ts super toxicity, it cannot be used as a drug itself. In recent cancer therapy developments, it is linked to a monoclonal antibody (mAb) that recognizes a pecific marker expression in cancer cells and directs MMAE to the cancer cells. The linker linking MMAE to the
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