Yohimbine Size:2mg solid NC1C=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)C(=O)N=1

NC1C=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)C(=O)N=1

is a highly potent and orally bioavailable PI3K/mTOR dual inhibitor developed through structure-based drug design

InChi: InChI=1S/C38H50N6O9S/c1-6-22-19-38(22

measured by loss of nuclear beta-catenin

H-PGDS INHIBITOR I has no code name

Yohimbine Size:2mg solid NC1C=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)C(=O)N=1Yohimbine is a potent and relatively nonselective alpha 2 adrenergic receptor (AR) antagonist, with IC50 of 0. 6 M. IC50 value: 0. 6 uM Target: alpha 2 adrenergic receptor in vitro: Yohimbine inhibits alpha2 receptor antagonist with Ki of 1. 05 nM, 1. 19 nM, and 1. 19 nM for 2A, 2B, 2C, respectively. Yohimbine also inhibits 5 HT1B with Ki of 19. 9 nM. Yohimbine acts to block the lowering of cAMP by alpha 2 adrenoceptor agonists. yohimbine actually