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selective inhibitor of VEGFR-2 tyrosine kinase (IC50 = 0
1396722-02-3 (deleted cas)
Solubility: DMSO: 57 mg/mL(199
so it has IC50 >1 µM for inhibiting demthylation of H3K4 in U2OS human osteosarcoma cell line and in human breast adenocarcinoma MCF7 tumor cell proliferation assay
Tumors of urinary bladder induced by cyclophosphamide (CP) in rats can be significantly reduced by Dimesna administration in a dose-related manner
Febuxostat 5132 selective inhibitor of VEGFR-2 tyrosineFebuxostat, also known as Uloric and TMX 67, is a xanthine oxidase inhibitor used to treathyperuricemia and chronic gout. Product information CAS Number: 144060 53 7 Molecular Weight: 316. 37 Formula: C16H16N2O3S Synonym: TEI 6720 TMX 67 Uloric FBX Chemical Name: 2 [3 cyano 4 (2 methylpropoxy)phenyl] 4 methyl 1,3 thiazole 5 carboxylic acid Smiles: CC1N=C(SC=1C(O)=O)C1=CC(C#N)=C(C=C1)OCC(C)C InChiKey: BQSJTQLCZDPROO UHFFFAOYSA N InChi: InChI=1S