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469(11):1443-1455
Formula: C21H25N3O6
Rapamycin is usually used at 1 µM final concentration in vitro and in cellular assays
1 and 1 mg/kg in both acute and delayed emesis models in ferrets
(2012) Nature Reviews Drug Discovery 11
Acetazolamide Size:10 mg solid 469(11):1443-1455Acetazolamide, also known as Diamox and PIM 005, is a carbonic anhydrase inhibitor that is sometimes effective against absence seizures. Acetazolamide is sometimes useful also as an adjunct in the treatment of tonic clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. Acetazolamide's antiepileptic effect may be due to its inhibitory effect on brain carbonic