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C646 was dosed to mice by Alzet pumps at 0
1-3H3/t15-/m1/s1
InChi: InChI=1S/C25H21FN6O2S/c26-17-2-1-3-19(10-17)31-25(34)30-18-6-4-15(5-7-18)21-14-35-23-20(12-28-24(27)22(21)23)16-11-29-32(13-16)8-9-33/h1-7
48 hours) inhibits BTK-transformed Ba/F3 cell proliferation with an IC50 of 11
which prevents both the binding of TGFb to its receptor TGFbR and TGFb-mediated signal transduction
Glucocorticoid receptor agonist-1 Size:Contact [email protected] for quotation C646 was dosed to miceGlucocorticoid receptor agonist 1 is a potent glucocorticoid receptor agonist with an IC50 of 2. 8 nM extracted from patent WO2017210471A1, compound 41. Product information CAS Number: 2166375 82 0 Molecular Weight: 569. 69 Formula: C35H39NO6 Chemical Name: (1S,2S,4R,6R,8S,9S,11S,12S,13R) 6 {4 [(3 aminophenyl)methyl]phenyl} 11 hydroxy 8 (2 hydroxyacetyl) 9,13 dimethyl 5,7 dioxapentacyclo[10. 8. 0. 0,. 0,. 0,]icosa 14,17 dien 16 one Smiles:
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