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ETC-159 is highly efficacious in molecularly defined colorectal cancers (CRCs) with R-spondin translocations
InChi: InChI=1S/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9
2010 Jan-Feb
and inhibits IClCa in RUICC without significantly affecting L-type Ca2+ current
Wnt inhibitor
Torin 2 Catalog No.:M10889-2 ETC-159 is highly efficacious inTorin 2 is a novel, second generation ATP competitive inhibitor that is potent and selective for mTOR with a superior pharmacokinetic profile to previous inhibitors ((EC50 = 0. 3 nM). It has been shown that Torin 2 displayed dramatic antiproliferative activity across a panel of cancer cell lines. Torin 2 showed a powerful cytotoxic activity, inhibiting the growth of each cell line in a dose dependent manner, with an IC in the nanomolar range. Torin 2
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