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Epub 2011 Aug 10
1'-biphenyl]-4-yl)-6-oxo-6
Woodrow MD
with an IC50 of ~50 nM with either substrate
Proteasome inhibition as a therapeutic strategy in patients with multiple myeloma
Mesna Size:Solid 2 mg Epub 2011 Aug 10Mesna is a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion. Check for active clinical trials or closed clinical trials
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