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4-Methylhistamine dihydrochloride Catalog No.:M22257-C CAS Number: 1046045-61-7

SKU: 75417976857

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Description

CAS Number: 1046045-61-7

InChi: InChI=1S/C17H17N3O3S/c1-10-5-4-6-18-15(10)9-24(22)17-19-13-7-11(2)12(16(21)23-3)8-14(13)20-17/h4-8H

PROTAC IRAK4 degrader-6 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1

Loriaux MM

Solubility: H2O : 33

4-Methylhistamine dihydrochloride Catalog No.:M22257-C CAS Number: 1046045-61-74 Methylhistamine dihydrochloride (or 4 methylhistamine) is a selective agonist of H4 receptor with a pEC50 value of 7. 40. 1 (=1) . In the chemotaxis of mast cells and leukocytes to sites of inflammation, the histamine H4 receptor (H4R) is involved . In transfected cells, 4 methylhistamine bound to hH4R with the highest affinity, compared to the binding to other histamine receptors. The interaction between 4 methylhistamine and hH4R showed a higher

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