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Formula: C22H29FO5
for 30 days) treatment extends survival in a severe SMA mouse model
4-dihydroquinazolin-4-one dihydrochloride
Cytotoxic activity of the MK2 inhibitor CMPD1 in glioblastoma cells is independent of MK2
InChi: InChI=1S/C26H26N2O2/c1-30-26(29)25(16-22-17-27-24-15-9-8-14-23(22)24)28(18-20-10-4-2-5-11-20)19-21-12-6-3-7-13-21/h2-15
3-(4-Pyridyl)indole Catalog No.:M22402-C Formula: C22H29FO53 (4 pyridyl)indole (Rockout) is a Rho kinase inhibitor . Rho associated protein kinase (ROCK) belongs to a family of serine threonine kinases mainly involved in regulating the shape and movement of cells by acting on the cytoskeleton . Rockout caused decreased migration and aberrant morphology. Rockout showed no effect on phagocytosis, listeria motility or actin polymerization in permeabilized yeast. In a human melanoma cell line M2 cells that blebs
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