MS31 trihydrochloride tenol sodium 4-dimethylpentanamido]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoic acid

4-dimethylpentanamido]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoic acid

InChiKey: XCFLWTZSJYBCPF-UHFFFAOYSA-N

Chemical Name: N-[(1R

pantoprazole

InChi: InChI=1S/C6H8O4

MS31 trihydrochloride tenol sodium 4-dimethylpentanamido]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoic acidMS31 trihydrochloride is a potent, highly affinity and selective fragment like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 trihydrochloride potently inhibits the interactions between SPIN1 and H3K4me3 (IC50=77 nM, AlphaLISA; 243 nM, FP). MS31 trihydrochloride selectively binds Tudor domain II of SPIN1 (Kd=91 nM). MS31 trihydrochloride potently inhibits binding of trimethyllysine containing peptides to SPIN1, and is not toxic to