Z-Asp-CH2-DCB - CAS# 153088-73-4 Size:2mg solid InChiKey: UHZBJJRBPXOONG-UHFFFAOYSA-N

InChiKey: UHZBJJRBPXOONG-UHFFFAOYSA-N

Signifor ditrifluoroacetate

and could offer benefits including a greater therapeutic index for treating T-cell malignancies

InChi: InChI=1S/C22H26N2O10/c25-18-4-3-17(20(28)23-18)24-21(29)15-2-1-14(13-16(15)22(24)30)34-12-11-33-10-9-32-8-7-31-6-5-19(26)27/h1-2

Its enantiomer (S)-PFI-2 is 500-fold less active making it an excellent negative control

Z-Asp-CH2-DCB - CAS# 153088-73-4 Size:2mg solid InChiKey: UHZBJJRBPXOONG-UHFFFAOYSA-NZ Asp CH2 DCB is an irreversible broad spectrum caspase inhibitor. Z Asp CH2 DCB also inhibits proteases with caspase like activity. Z D CH2 DCB blocks the production of IL 1, TNF , IL 6, and IFN in staphylococcal enterotoxin B (SEB) stimulated peripheral blood mononuclear cells (PBMC), and reduces SEB 1 stimulated T cell proliferation in a dose dependent manner. Z Asp CH2 DCB prevents SU5416 induced septal cell apoptosis and emphysema development.