1, 4-Chrysenequinone E 5729 PT2385 exhibits good mouse oral

PT2385 exhibits good mouse oral bioavailability (110%) and low to medium in vivo clearance

is a competitive FtsZ polymerization and GTPase activity (Ki of 31

The EC50s are 1

1-2H3/t18-

Smiles: CC1=CC=C(C=C1Br)NC1=NN=C(CC2C=CN=CC=2)C2=CC=CC=C21

1, 4-Chrysenequinone E 5729 PT2385 exhibits good mouse oral1,4 Chrysenequinone, a polycyclic aromatic quinone, acts as an activator of aryl hydrocarbon receptor (AhR). Product information CAS Number: 100900 16 1 Molecular Weight: 258. 27 Formula: C18H10O2 Synonym: Chrysene 1,4 dione Chemical Name: 1,4 dihydrochrysene 1,4 dione Smiles: O=C1C=CC(=O)C2C=CC3C4=CC=CC=C4C=CC=3C1=2 InChiKey: UORKIKBNUWJNJF UHFFFAOYSA N InChi: InChI=1S C18H10O2 c19 16 9 10 17(20)18 14 6 5 11 3 1 2 4 12(11)13(14)7 8 15(16)18 h1 10H