8-Oxoepiberberine sine dihydrochloride Smiles: CC(C)N(C(C)C)P(O[C@H]1[C@@H](OC)[C@@H](O[C@@H]1COC(C1C=CC=CC=1)(C1C=CC(=CC=1)OC)C1C=CC(=CC=1)OC)N1C=NC2C1=NC=NC=2NC(=O)C1C=CC=CC=1)OCCC#N

Smiles: CC(C)N(C(C)C)P(O[C@H]1[C@@H](OC)[C@@H](O[C@@H]1COC(C1C=CC=CC=1)(C1C=CC(=CC=1)OC)C1C=CC(=CC=1)OC)N1C=NC2C1=NC=NC=2NC(=O)C1C=CC=CC=1)OCCC#N

2 and the IC50 was 11

3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-5-[(diaminomethylidene)amino]pentanamido]-3-methylbutanamido]-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carboxylic acid

13R)-24-methyl-5

Smiles: CC1N=C(NCCCCCCC2C=CC=CC=2)N=C(C)C=1O

8-Oxoepiberberine sine dihydrochloride Smiles: CC(C)N(C(C)C)P(O[C@H]1[C@@H](OC)[C@@H](O[C@@H]1COC(C1C=CC=CC=1)(C1C=CC(=CC=1)OC)C1C=CC(=CC=1)OC)N1C=NC2C1=NC=NC=2NC(=O)C1C=CC=CC=1)OCCC#N8 Oxoepiberberine is an alkaloid metabolite in the plasma after oral administration of Zuojin formula, a traditional chinese medicine used to treat gastrointestinal disease. Product information CAS Number: 19716 60 0 Molecular Weight: 351. 35 Formula: C20H17NO5 Chemical Name: 16,17 dimethoxy 5,7 dioxa 1 azapentacyclo[11. 8. 0. 0,. 0,. 0,]henicosa 3,8,10,12,14(19),15,17 heptaen 2 one Smiles: COC1=CC2CCN3C(=O)C4=C5OCOC5=CC=C4C=C3C=2C=C1OC InChiKey: