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Tyrphostin AG 112 is an EGFR phosphorylation inhibitor
The drug was approved by the European Medicines Agency in November 2011 and by the Japanese Pharmaceuticals and Medical Devices Agency in September 2013
Crizotinib (PF-02341066) hydrochloride (Xalkori) inhibits tyrosine phosphorylation of c-Met and nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) with IC50 of of 11 nM and 24 nM in cell-based assays
CC1=CC(=C(C=C1C(=O)NC(N)=N)S(C)(=O)=O)S(C)(=O)=O
InChiKey: XYKZSUXWBGUGQV-UHFFFAOYSA-N
L-Aspartic aicd sodium Catalog No.:M30314-C Tyrphostin AG 112 is anL Aspartic aicd sodium is is an amino acid, shown to be a suitable prodrug for colon specific drug deliverly. Product information CAS Number: 3792 50 5 Molecular Weight: 155. 08 Formula: C4H6NNaO4 Chemical Name: sodium (2S) 2 amino 3 carboxypropanoate Smiles: [Na+]. N[C@@H](CC(O)=O)C([O ])=O InChiKey: WTWSHHITWMVLBX DKWTVANSSA M InChi: InChI=1S C4H7NO4. Na c5 2(4(8)9)1 3(6)7; h2H,1,5H2,(H,6,7)(H,8,9); q;+1 p 1 t2 ; m0. s1 Technical Data Appearance:
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