![Purvalanol B - CAS# 212844-54-7 10691 Smiles: C[C@]12CC[C@H]3[C@@H](CC[C@H]4N(C)C(=O)C(F)=C[C@@]43C)[C@@H]1CC[C@@H]2C(=O)NCC1NC2=CC=CN=C2N=1](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M11323_1621563366.gif?v=1742887066)
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Smiles: C[C@]12CC[C@H]3[C@@H](CC[C@H]4N(C)C(=O)C(F)=C[C@@]43C)[C@@H]1CC[C@@H]2C(=O)NCC1NC2=CC=CN=C2N=1
6 nM and 5
for which it received orphan drug status from the U
CAS Number: 6892-68-8
5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3
Purvalanol B - CAS# 212844-54-7 10691 Smiles: C[C@]12CC[C@H]3[C@@H](CC[C@H]4N(C)C(=O)C(F)=C[C@@]43C)[C@@H]1CC[C@@H]2C(=O)NCC1NC2=CC=CN=C2N=1Purvalanol B, also known as NG 95, is a potent and selective CDK inhibitor that most potently inhibits Cdk2 cyclin A, Cdk2 cyclin E, Cdk5 p35, and Cdk2 cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively). Product information CAS Number: 212844 54 7 Molecular Weight: 432. 90 Formula: C20H25ClN6O3 Synonym: NG 95 NG95 NG 95 Chemical Name: 2 chloro 4 [(2 {[(2R) 1 hydroxy 3 methylbutan 2 yl]amino} 9 (propan 2 yl) 9H purin 6 yl)amino]benzoic acid Smiles: