MK-2461 1762 Molecular Weight: 783

Molecular Weight: 783

Gouni-Berthold I

Rimantadine is an orally administered antiviral drug used to treat

or 10 mg/kg zVAD groups

CAS Number: 919091-63-7

MK-2461 1762 Molecular Weight: 783MK 2461 is a novel ATP competitive multitargeted inhibitor of activated c Met with a mean IC50 of 2. 5 nM. IC50 value: 2. 5 nM Target: c Metin vitro: MK 2461 inhibits the kinase activity of human c Met with a mean IC50 of 2. 5 nM in the presence of 50 M ATP. Ron (IC50 = 7 nM) and Flt1 (IC50 = 10 nM) are inhibited by MK 2461 with similar potencies to c Met (IC50 = 2. 5 nM), whereas nine other kinases, including FGFR1, FGFR2, FGFR3, PDGFR, KDR, Flt3,