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Chemical Name: 8-[(2R)-1-(3
tolerability and clinical activity of VX-765
3-b]pyridin]-6-yl]acetamide hydrochloride
Formula: C23H18N8
the two ways of administration are observed with quick absorption (Tmax)
ZX-29 Size:Contact [email protected] for quotation Chemical Name: 8-[(2R)-1-(3ZX 29 is a potent and selective ALK inhibitor with an IC50 of 2. 1 nM, 1. 3 nM and 3. 9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively. ZX 29 is inactive against EGFR. ZX 29 induces apoptosis by inducing endoplasmic reticulum (ER) stress and overcomes cell resistance caused by an ALK mutation. ZX 29 also induces protective autophagy and has antitumor effect. Product information CAS Number: 2254805 62 2 Molecular Weight: 518. 03 Formula:
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