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Chemical Name: 4-{ethyl[1-(4-methoxyphenyl)propan-2-yl]amino}butan-1-ol
Following DOT1L inhibition
367–371 (1985)
thereby ameliorating muscle wasting in the hypermetabolic state of cancer cachexia
Chemical Name: 5-chloro-4-(1H-indol-3-yl)-N-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidin-2-amine
Tariquidar 60314 Chemical Name: 4-{ethyl[1-(4-methoxyphenyl)propan-2-yl]amino}butan-1-olTariquidar, also known as XR9576, is a P glycoprotein (P gp) inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non competitively binds to the p glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity. Product information CAS
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