Alisol B 23-acetate PEG1-C2-Boc InChi: InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h9-10

Name: Alisol B 23-acetate PEG1-C2-Boc InChi: InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h9-10
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SKU: 57099283317

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Description

InChi: InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h9-10

2007 Jan 11

Chemical Name: 4-carbamothioylphenyl 2-(6-methoxynaphthalen-2-yl)propanoate

InChiKey: VSZGPKBBMSAYNT-RRFJBIMHSA-N

12740 μg/L by IV and PO respectively

Alisol B 23-acetate PEG1-C2-Boc InChi: InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h9-10Alisol B 23 acetate (23 Acetylalismol B), a natural triterpenoid, produces protective effects against EE induced cholestasis, due to FXR mediated gene regulation. IC50 Value: Target: Anti hepatotoxic natural product. In vitro: Alisol B 23 acetate has an effect on FXR activation in a dose dependent manner using luciferase reporter assay in HepG2 cells . In vivo: In alisol B 23 acetate treated mice, the changes in transporters and enzymes, as well as

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