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and good exposure in humans
Chemical Name: (3S)-3-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S
[O-]S(=O)(=O)C1CC(=O)N(OC(=O)CCCCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)C1=O
J Allergy Clin Immunol
Inhibitor is a novel stearoyl-CoA desaturase1 (SCD1) inhibitor
Dehydrocorydaline 02 Hydrochloride and good exposure in humansDehydrocorydaline (13 Methylpalmatine) is an alkaloid isolated from traditional Chinese herb Corydalis yanhusuo W. T. Wang. Dehydrocorydaline regulates protein expression of Bax, Bcl 2; activates caspase 7, caspase 8, and inactivates PARP. Dehydrocorydaline elevates p38 MAPK activation. Anti inflammatory and anti cancer activities. Dehydrocorydaline shows strong anti malarial effects (IC50 =38 nM), and low cytotoxicity (cell viability > 90%) using P.
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