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Johnston K
6'-O-β-Apiofuranosylsweroside is a secoiridoid glycoside that can be isolated from the leaves of Lonicera angustifolia Wall
24(12):2291
Solubility: DMSO: 35 mg/mL(200
InChiKey: OINVVPOIGFSNHM-VLIAUNLRSA-N
PF-06372865 Catalog No.:M14974-2 Johnston KPF 06372865 is an orally active, 2 3 5 subtype selective GABAA positive allosteric modulator (PAM). PF 06372865 is a high affinity ligand at GABAA receptors containing 1 2 3 5 subunits (Kis of 2. 9 nM, 21 nM, 134 nM for 2, 1 PAM, 2 PAM, respectively), with low affinity for 4 6 subunits. PF 06372865 can across the blood brain barrier (BBB). PF 06372865 has anxiolytic activity and has the potential for epilepsy. Product information CAS Number: 1614245
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