Ferrostatin-1 - Fer-1, Ferroptosis Inhibitor. CAS# 347174-05-4 size:2mg solid and the chemo-proteomics approach demonstrated

and the chemo-proteomics approach demonstrated the superior selectivity of TMP269 relative to the other hydroxamate-substituted analogs via a chelating zinc-binding group

Hydroxychloroquine Destabilizes Phospho-S6 in Human Renal Carcinoma Cells

UNC0379 was used at 10-30 µM in vitro assays

Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: effects of linker technology on efficacy and toxicity

BAY11 enhances OCT4 synthetic mRNA expression in adult human skin cells

Ferrostatin-1 - Fer-1, Ferroptosis Inhibitor. CAS# 347174-05-4 size:2mg solid and the chemo-proteomics approach demonstratedFerrostatin 1 (Fer 1), CAS No. 347174 05 4 , is a potent inhibitor of ferroptosis with an EC50 ~60 nM, identified by a HTS using erastin induced ferroptosis in HT 1080 cells. Ferroptosis is a unique iron dependent form of nonapoptotic cell death triggered by the oncogenic RAS selective lethal small molecule erastin. Ferroptosis is dependent upon intracellular iron, but not other metals, and is morphologically, biochemically, and genetically distinct