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IOX1 inhibits JMJD2A-mediated H3K9me3 demethylation in HeLa cells
CAS Number: 802906-73-6
HDAC7 and HDAC9 respectively
IWR-1 exerts its effect via interaction with Axin
8 μM across a selected panel of cancer cell lines
PF-00562271 EG5-Tos IOX1 inhibits JMJD2A-mediated H3K9me3 demethylationPF 562271, also known as PF 562, 271 and PF 271, is an orally bioavailable small molecule and ATP competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities. PF 562271 inhibits the tyrosine kinase FAK, and to a lesser extent, proline rich tyrosine kinase (PYK2), which may inhibit tumor cell migration, proliferation, and survival. Product information CAS Number: 717907 75 0 Molecular Weight: 507. 49
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