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3)26-19(27)25-17-15(8-12-10-22-18(21)24-16(12)23-17)11-6-13(28-4)9-14(7-11)29-5/h6-10H
HK420 methylation has been implicated in the regulation of a variety of biological processes including the DNA damage response
Nutlin-3 is an inhibitor of MDM2 (human homolog of murine double minute 2)
At 100 μM Apoptosis Activator 2 exhibited 100% cytotoxicity in virtually all cell lines
Smiles: NC1C=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)C(=O)N=1
Cobimetinib (R) - CAS# 934660-94-3 0305 3)26-19(27)25-17-15(8-12-10-22-18(21)24-16(12)23-17)11-6-13(28-4)9-14(7-11)29-5/h6-10HCobimetinib (R) is the less active R enantiomer of Cobimetinib. Cobimetinib is a potent and selective MEK inhibitor. Product information CAS Number: 934660 94 3 Molecular Weight: 531. 31 Formula: C21H21F3IN3O2 Synonym: GDC 0973 R enantiomer XL 518 R enantiomer Chemical Name: 1 {3,4 difluoro 2 [(2 fluoro 4 iodophenyl)amino]benzoyl} 3 [(2R) piperidin 2 yl]azetidin 3 ol Smiles: OC1(CN(C1)C(=O)C1=CC=C(F)C(F)=C1NC1=CC=C(I)C=C1F)[C@H]1CCCCN1 InChiKey:
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