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6 nM in A431 cells
Kinoshita M
but not hematopoietic stem cells
RK-33 binds specifically to DDX3
2015 Dec 9
Ribavirin e Hydrochloride 6 nM in A431 cellsRibavirin is an anti viral drug used for severe RSV infection; hepatitis C infection, including if persistent, and often in combination with peginterferon alfa 2b or peginterferon alfa 2a; as well as some other viral infections. It is a guanosine (ribonucleic) analog used to stop viral RNA synthesis and viral mRNA capping, thus, it is a nucleoside inhibitor. Ribavirin is a prodrug, which when metabolized resembles purine RNA nucleotides. In this form
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