Lysine-specific Demethylase Inhibitor (1C) orine hydrochloride Smiles: [2H]C([C@]([2H])(NC(=O)[C@@H](NC)C(C)C)C(=O)N(C)[C@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)C1C=CC=CC=1)OC)[C@@H](C)CC)(C([2H])([2H])[2H])C([2H])([2H])[2H]

Smiles: [2H]C([C@]([2H])(NC(=O)[C@@H](NC)C(C)C)C(=O)N(C)[C@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)C1C=CC=CC=1)OC)[C@@H](C)CC)(C([2H])([2H])[2H])C([2H])([2H])[2H]

3-dihydro-1H-indol-5-yl]ethyl]benzamide

CAS Number: 18085-97-7

CAS Number: 732983-37-8

Molecular Weight: 433

Lysine-specific Demethylase Inhibitor (1C) orine hydrochloride Smiles: [2H]C([C@]([2H])(NC(=O)[C@@H](NC)C(C)C)C(=O)N(C)[C@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)C1C=CC=CC=1)OC)[C@@H](C)CC)(C([2H])([2H])[2H])C([2H])([2H])[2H]Lysine specific Demethylase Inhibitor (1C) is a lysine specific demethylase inhibitor. Lysine specific demethylase 1 (LSD1) is the first of several protein lysine demethylases identified. Through a FAD dependent oxidative reaction, LSD1 could specifically remove histone H3K4me2 to H3K4me1 or H3K4me0. When forming a complex with androgen receptor, LSD1 alters its substrates to H3K9me2. The LSD1 complex regulates a coordinated histone modification