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GSK-923295 - CAS# 1088965-37-0 size:2mg solid 20)12-9-13(21)22-10-11(12)14-23-15(26-1-5-28-6-2-26)25-16(24-14)27-3-7-29-8-4-27/h9-10H

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Description

20)12-9-13(21)22-10-11(12)14-23-15(26-1-5-28-6-2-26)25-16(24-14)27-3-7-29-8-4-27/h9-10H

BMS-56224701

(2013) Cancer Med

Chemical Name: 6H-Thieno[3

Am J Physiol Cell Physiol

GSK-923295 - CAS# 1088965-37-0 size:2mg solid 20)12-9-13(21)22-10-11(12)14-23-15(26-1-5-28-6-2-26)25-16(24-14)27-3-7-29-8-4-27/h9-10HGSK 923295, CAS No. 1088965 37 0, also known as GSK 923295A, is a novel antimitotic inhibitor of centromere associated protein E (CENP E) with potential anticancer activity. GSK 923295A demonstrated significant antitumor activity against solid tumor models, inducing CRs in Ewing sarcoma, rhabdoid, and rhabdomyosarcoma xenografts. Clinical study showed that GSK 923295 had dose proportional pharmacokinetics and a low number of grade 3 or 4 adverse

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