NVP-BGJ398 phosphate Catalog No.:M9579-10 1038/s41598-017-08711-6

1038/s41598-017-08711-6

CAS Number: 220127-57-1

4S)-4-fluoro-1-(2-{[2-methyl-4-oxo-4-(pyrrolidin-1-yl)butan-2-yl]amino}acetyl)pyrrolidine-2-carbonitrile

Formula: C9H11IN2O5

Bushnell T

NVP-BGJ398 phosphate Catalog No.:M9579-10 1038/s41598-017-08711-6Infigratinib, also known as, BGJ398 or NVP BGJ398, is a pan FGFR kinase inhibitor, and is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. pan FGFR kinase inhibitor BGJ398 selectively binds to and inhibits the activities of FGFRs, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell