Cathepsin S inhibitor 801653 dihydrochloride Chemical Name: 2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1

Chemical Name: 2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1

are significantly lower than the IC50 values calculated for cells cultured in the presence of PAI-039 under attached condition

is a potent phosphoinositide 3-kinase (PI3K) inhibitor

16)14-10-12-6-1-7-13-10/h1-7H

The mean inhibitory concentration (MIC) of Tigecycline for E

Cathepsin S inhibitor 801653 dihydrochloride Chemical Name: 2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1LY3000328 is a Cathepsin S inhibitor with excellent in vitro potency and selectivity against other cysteine proteases. LY3000328 is currently in clinical trials. Cathepsin S (Cat S) plays an important role in many pathological conditions, including abdominal aortic aneurysm (AAA). Inhibition of Cat S may provide a new treatment for AAA. Product information CAS Number: 1373215 15 6 Molecular Weight: 484. 52 Formula: C25H29FN4O5 Chemical Name: (3R,4S) 4