RNF5 inhibitor inh-02 ophosphoric acid disodium salt hydrate (α and β mixture) CAS Number: 1334546-77-8

CAS Number: 1334546-77-8

covalent and orally active inhibitor of KRAS G12C with IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells

3-diyl dicarbamate

Callebaut C

Small-molecule inhibition of pyruvate phosphate dikinase targeting the nucleotide binding site

RNF5 inhibitor inh-02 ophosphoric acid disodium salt hydrate (α and β mixture) CAS Number: 1334546-77-8RNF5 inhibitor inh 02 is a potent inhibitor of E3 ubiquitin ligase RNF5 RMA1. RNF5 inhibitor inh 02 leads to significant F508del CFTR rescue (EC50=2. 2 uM) in bronchial epithelial cells homozygous for the F508del mutation. RNF5 inhibitor inh 02 can be used for cystic fibrosis research. Product information CAS Number: 324579 65 9 Molecular Weight: 384. 50 Formula: C23H20N4S Chemical Name: N (4 benzyl 3 methyl 4,5 dihydro 1,2,4 thiadiazol 5 ylidene) N'