DMP 777 - CAS# 157341-41-8 oxacin(DU 6859A) OC(=O)CCCC1C=CC=CC=1 |^1:0|

OC(=O)CCCC1C=CC=CC=1 |^1:0|

which was reported in J Med Chem

CAS Number: 1235403-62-9

CAS Number: 781661-94-7

Meropenem was originally developed by Sumitomo Pharmaceuticals

DMP 777 - CAS# 157341-41-8 oxacin(DU 6859A) OC(=O)CCCC1C=CC=CC=1 |^1:0|DMP 777 also known as L 694458, is a potent and orally active Leukocyte elastase (HLE) inhibitor. Oral dosing with DMP 777 caused a rapid increase in serum gastrin levels and severe hypochlorhydria. DMP 777 inhibited aminopyrine accumulation into rabbit parietal cells stimulated with either histamine or forskolin. DMP 777 reversed a stimulated proton gradient in isolated parietal cell tubulovesicles. DMP 777 acts as a protonophore with specificity for