Pay in 4 interest-free payments of $30.00 Learn more
Ships within 48 hours · Estimated delivery Aug 7 - Aug 12
PubMed PMID: 26738988
CAS Number: 1616413-96-7
InChiKey: ZRJBHWIHUMBLCN-SEQYCRGISA-N
Epub 2014 Feb 4
MI-2 concentrated within human ABC-DLBCL cells and irreversibly inhibited cleavage of MALT1 substrates with EC50 < 1 µM (HBL-1 ~200 nM
CZC-54252 443 PubMed PMID: 26738988CZC 54252 is a potent inhibitor of leucine rich repeat kinase 2 (LRRK2) with IC50 values 1. 28 nM and 1. 85 nM for wild type and G2019S mutant forms of LRRK2 respectively. CZC 54252 attenuates neuronal injury induced by LRRK2 G2019S mutant activity in primary human neurons (EC50 = 1 nM). Activating mutations in leucine rich repeat kinase 2 (LRRK2) are present in a subset of Parkinson's disease (PD) patients and may represent an attractive therapeutic
US$ 120.00
US$ 36.00
US$ 38.00
US$ 114.00
US$ 22.00
US$ 38.00