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32(3):799-806
15(8):1467-76
PubMed PMID: 21249167
2019 Feb 21
PC3 and MES-SA at a dose of 10-20 mg/kg
VX-770 Size:2mg solid 32(3):799-806VX 770, is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 45% cases of cystic fibrosis, and is included in a combination drug, lumacaftor ivacaftor, which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR. Ivacaftor is a "potentiator" of CFTR, meaning it increases the probability that the defective channel
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