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Suchankova T
and pS6 in all the cell lines
which inhibits ATR immunoprecipitated from HeLa nuclear extracts with an IC50 of 5 nM and ATR mediated phosphorylation of Chk1 in HT29 colorectal adenocarcinoma tumor cells with an IC50 of 50 nM
Consistent with the activation of the Gqα-mediated signaling pathway
InChi: InChI=1S/C42H68N6O10/c1-29(47(5)41(53)58-42(2
GW9508 - selective FFA1 GPR40 agonist. CAS# 885101-89-3 P50469 Suchankova TGW9508 is a potent and selective agonist for FFA1 (GPR40) with pEC50 of 7. 32, 100 fold selective against GPR120, stimulates insulin secretion in a glucose sensitive manner. Product information CAS Number: 885101 89 3 Molecular Weight: 347. 41 Formula: C22H21NO3 Chemical Name: 3 (4 ((3 phenoxybenzyl)amino)phenyl)propanoic acid Smiles: OC(=O)CCC1C=CC(=CC=1)NCC1=CC(=CC=C1)OC1C=CC=CC=1 InChiKey: DGENZVKCTGIDRZ UHFFFAOYSA N InChi: InChI=1S C22H21NO3 c24
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